• Proheart 6/12 Injectable for Dogs


  • Bravecto Plus Spot-On for Cats (with Fluralaner)
  • Advocate/Advantage Multi Spot-On for Dogs and Cats (with Imidacloprid)


Uses of Moxidectin

Moxidectin is an ectoparasiticide an endoparasiticide used to treat internal parasites and limited external parasites in dogs and cats.

For dogs: Used to prevent heartworm disease, and control roundworms, hookworms, whipworms and mites.

For cats: Used to prevent heartworm disease, and control roundworms, hookworms, and ear mites.

Moxidectin has no effect against tapeworms, fleas or ticks. It is often combined with イミダクロプリド to include protection against fleas.


Subcutaneous application for dogs only.

Combined ingredient products available as external application, supplied as topical/spot-on solution.


Moxidectin injections are only for administration by a veterinarian. Combined ingredient products are available for home use.

Injections are a sustained release solution that provide protection for 6 or 12 months, depending on the product.

Moxidectin should be administered within one month of the animal’s first exposure to mosquitoes and continued until a month after the last exposure to mosquitoes. In areas where mosquitoes are present at all time, Moxidectin treatment may continue year-round without interruption.

As with all heartworm preventatives, dogs should be tested and cleared for existing heartworm before treatment begins.


Reported side effects in dogs treated with Moxidectin include loss of coordination, lethargy, loss of appetite, vomiting and diarrhea.

Transient swelling may occur at the site of injection.

Potential side effects will vary when using products with additional active ingredients.


Moxidectin injections are for administration by certified veterinary staff only.

Collies and related breeds have increased sensitivity to Moxidectin. Dosing with these dogs must be as accurate as possible.

Subcutaneous application of Moxidectin is not suitable for cats.


Signs of Moxidectin overdose include extreme dilation of the pupils (contraction in cats), weakness, hypothermia, drooling, vomiting, breathing difficulties and seizures.

If you suspect your dog or cat has had an overdose, please contact your veterinarian immediately.


This information is provided for general reference only and is not intended to replace the packaging label or veterinary advice. This page may not include all side effects, uses, brand names or applications.


Moxidectin drug information sheet
Moxidectin Information Sheet






How to replace dogs’ problem behaviors using differential reinforcement

Many dog owners struggle with their pets’ bad habits, but do not want to punish them. Differential reinforcement offers another option. How to replace dogs’ problem behaviors using differential reinforcement Many dog owners struggle with their companions’ problem behaviors, but do not like the idea of punishing their pets. Fortunately for pet parents, differential reinforcement swaps bad behaviors for better ones without the need to scold your four-legged friend. Differential reinforcement is a complex name for a relatively simple concept: By replacing problem behaviors with more desirable actions, you can reduce bad behaviors in pets. This is done through positive reinforcement of incompatible behaviors, or actions that cannot take place at the same time as  the undesired habit. By rewarding the more desirable action, you make it easy for your pet to choose the preferable behavior, reducing bad habits without ever needing to punish your pet. To start differential reinforcement of other behavior, it is crucial to pick a replacement behavior that cannot take place at the same time as the unwanted habit. For example, if your dog is prone to jumping on guests as they enter your home, you may choose the “sit” command as your alternative. Start your pet’s practice in a quiet spot with very few distractions and no other people. As he begins to master the alternative commend in this setting, slowly add distractions to his training. You can do this by practicing in your backyard, during walks, and even in a dog park. Eventually, when you feel confident Fido has mastered the command, you can practice in the scenario that triggers his problem behavior. Begin this phase of training with your dog on a leash to help maintain control over the environment, as allowing him to continue a problem behavior only reinforces the habit. Likewise, even negative attention such as scolding can be a reward to some pets, so avoid reinforcing any unwanted actions as much as possible. In the example above, this means asking guests to turn away and not acknowledge your pet if he begins to jump on them. Instead, ask your dog to sit and as soon as he performs the command, reward him with treats, praise and attention. This will be especially effective if you use high-value treats such as meat or cheese during the early stages of training. As with any training, practice makes perfect. It is common to experience setbacks as you introduce the alternative behavior in trigger situations, so be patient with your pet. It may take more than a few attempts to achieve the desired outcome, so do not push your pet too hard during any given training session, as you and your dog will both lose focus and become frustrated. Over time, your companion should learn to seek the reward rather than repeat bad habits, replacing problem behaviors with more desirable actions.


屋内の猫は長生きしますが、余分な体重を詰め込む傾向があります。キティが徐々に体重を減らすのに役立ついくつかのヒントがあります。あなたの猫が体重を減らすのを助ける方法あなたの猫を屋内に保つことは彼がより長い人生を送るのを助けることができます、しかし家猫は体重増加の問題につながることができるより座りがちなライフスタイルになりがちです。キティを健康的な体重に保つために、栄養豊富な食べ物、慎重に検討された部分、活動や遊びを刺激するインタラクティブなおもちゃをキティに提供することで、彼の食事とライフスタイルを再考する必要があるかもしれません。ペットの減量プログラムを開始する前に、健康的なダイエットをサポートし、厳しい食事制限を回避する計画を立てることについて獣医に相談してください。急激な体重減少は、脂肪肝疾患と呼ばれる深刻な病気を猫に引き起こす可能性があるため、これは猫を減量プログラムに入れるときにスキップする必要のある手順ではありません。あなたの獣医が計画を承認したら、あなたはあなたのペットの健康的な体重を達成するために働き始めることができます。 「健康」とは動物ごとに異なりますが、ペットの体を使ってコンパニオンのベースラインを確立することができます。猫の体調の客観的な尺度は、猫の肋骨とはっきりとしたウエストラインが見えるかどうか、ペットの骨の構造をどれだけ簡単に感じることができるかなど、観察可能な特徴に基づいています。健康的な体重では、猫の腰が肋骨の後ろに見えるはずです。彼の肋骨を感じますが、見えません。そして彼の胃の脂肪の小さなポーチを観察します。猫は1週間で体重の2%を超えて減らさないようにする必要があるため、過剰な体重を減らすことは段階的なプロセスである必要があります。獣医師は、キティが健康的な体重を達成するのに役立つカロリー目標と給餌スケジュールの計算を支援できますが、食事の種類の変更などの小さな変更を通じて、彼が体重を減らすのを手伝うことができます。たとえば、食物繊維が多く脂肪が少ない食事は、ペットが過剰なカロリーなしでより多くの量の食物を摂取できるようにすることで、ペットがより長く満腹感を感じるのに役立ちます。同様に、高タンパク、低炭水化物ダイエットは、ペットがより長く満腹感を感じるのを助け、体重減少に貢献することができます。水分含有量の多いウェットフードを選択すると、カロリーを消費せずにキティの部分の量を増やすことで減量に役立ちます。ペットの栄養豊富な餌を管理された量で与えることに加えて、よりアクティブなライフスタイルをサポートすることで、ペットが徐々に体重を減らすのを助けることができます。屋内での生活は猫の平均余命を延ばし、屋外のペットの餌食となる鳥などの野生生物を保護しますが、飼い猫は活動性が低く、余分な体重がかかる傾向があります。レーザーポインターや釣り竿などのおもちゃを使ってペットと遊ぶことで、ペットがより活発になるのを助けることができます。彼にパズルフィーダーを与えて、彼の体と心の両方に挑戦します。または、猫の木や窓辺のとまり木など、ジャンプや登山のためのより多くの垂直スペースを彼に提供します。健康的な食事と部分を組み合わせることで、これはあなたのペットが制御された方法で不健康な体重を減らすのを助けることができます。


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